Applications relating to biological material are subject to the special provisions set out in Rule 28. In accordance with Rule 23b(3), the term "biological material" means any material containing genetic information and capable of reproducing itself or being reproduced in a biological system. If an invention involves the use of or concerns biological material which is not available to the public and which cannot be described in the European patent application in such a manner as to enable the invention to be carried out by a person skilled in the art, the disclosure is not considered to have satisfied the requirements of Art. 83 unless the requirements of Rule 28(1), (2), first and second sentences, and (3), first sentence, have been met.